Higher Tier - Grades 4-9

GCSE Biology Higher Short Paper B

Covers Respiration and Exercise, The Nervous System and Reflexes, Hormones and Homeostasis and 3 more.

8 questions - 40 marks - calculator allowed

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Questions

Question 1 [4 marks]

Genetics and Inheritance

In snapdragon plants, flower colour shows codominance. The allele for red flowers (R) and the allele for white flowers (W) are both expressed if present together, producing pink flowers.

A red-flowered plant (RR) is crossed with a white-flowered plant (WW). Use a genetic diagram to determine the genotype and phenotype of all the offspring, and explain why this phenotype appears.

Question 2 [4 marks]

Hormones and Homeostasis

A patient's blood glucose concentration was 5.5 mmol/l at 08:00 and rose to 9.5 mmol/l at 08:30 after breakfast.

Calculate the mean rate of increase in blood glucose concentration, in mmol/l per minute, over this time.

Question 3 [4 marks]

Ecosystems and Material Cycles

A student estimates the population of snails in a garden using the mark-release-recapture method. On the first day, 40 snails are caught, marked, and released. The next day, 50 snails are caught, of which 8 are found to be marked.

Calculate an estimate of the total population of snails in the garden, using population estimate = (number marked in first sample x total number in second sample) / number of marked individuals recaptured.

Question 4 [5 marks]

The Nervous System and Reflexes

A student repeated a computer reaction time test five times, recording (in seconds): 0.31, 0.29, 0.33, 0.58, 0.30.

Identify the anomalous result and explain why it should be excluded, then calculate the mean reaction time using the remaining four results.

Question 5 [5 marks]

Genetics and Inheritance

In humans, sex is determined by the sex chromosomes: XX in females and XY in males.

Using a genetic diagram, explain why the probability of a baby being born male is normally about 50%.

Question 6 [6 marks]

Evolution and Natural Selection

Two populations of the same species become separated by a new river, and cannot interbreed for many thousands of years.

Explain how this separation could eventually lead to the formation of two separate species, and explain how scientists could use DNA evidence to confirm that speciation has occurred.

Question 7 [6 marks]

Respiration and Exercise

Aerobic respiration of one mole of glucose releases about 2900 kJ of energy. Anaerobic respiration (producing lactic acid) of one mole of glucose releases only about 120 kJ of energy.

Calculate how many times more energy is released by aerobic respiration than anaerobic respiration of the same amount of glucose, and explain why muscle cells still respire anaerobically during vigorous exercise despite this being far less efficient.

Question 8 [6 marks]

The Nervous System and Reflexes

Explain, in terms of the lens and ciliary muscles, how the eye focuses on a near object rather than a distant object.

Model solutions

Mark scheme for Question 1 [4 marks]
Question 1[4 marks]
Answer or workingMarks
a correctly completed genetic diagram (Punnett square) crossing RR with WWM1
all offspring having the genotype RWA1
all offspring having a pink phenotypeA1
explaining that because R and W are codominant, both alleles are expressed together in a heterozygous plant, producing a blended pink phenotype rather than a plant being purely red or whiteB1
Final answer: All offspring have the genotype RW and a pink phenotype, because in codominance both the red and white alleles are expressed together
Mark scheme for Question 2 [4 marks]
Question 2[4 marks]
Answer or workingMarks
finding the change in concentration = 9.5 - 5.5 = 4 mmol/lM1
identifying the time taken = 30 minutesM1
using rate = change / timeM1
a rate of 4/30 = 0.13 mmol/l per minute (2 significant figures)A1
Final answer: 0.13 mmol/l per minute
Mark scheme for Question 3 [4 marks]
Question 3[4 marks]
Answer or workingMarks
using the given formula, population estimate = (number marked in first sample x total in second sample) / number recaptured markedM1
substituting (40 x 50) / 8M1
calculating 40 x 50 = 2000M1
250 snailsA1
Final answer: An estimated population of 250 snails
Mark scheme for Question 4 [5 marks]
Question 4[5 marks]
Answer or workingMarks
identifying 0.58 seconds as the anomalous resultB1
explaining it is much higher than (does not fit the pattern of) the other four results, likely reflecting an error such as a lapse in concentration rather than a genuine reaction timeB1
summing the remaining four results (0.31 + 0.29 + 0.33 + 0.30 = 1.23)M1
dividing the sum by 4M1
a mean reaction time of 0.31 seconds (2 significant figures)A1
Final answer: 0.58 s is anomalous and should be excluded; the mean of the remaining four results is 0.31 seconds (2 s.f.)
Mark scheme for Question 5 [5 marks]
Question 5[5 marks]
Answer or workingMarks
the mother's eggs all carry an X chromosomeB1
the father's sperm carry either an X chromosome or a Y chromosome, in roughly equal numbersB1
a correctly completed genetic diagram (Punnett square) showing XX, XX, XY, XY offspringM1
2 out of 4 (or 1 out of 2) combinations are XY (male)A1
this gives a probability of about 50% for each sex at each fertilisationB1
Final answer: Eggs always carry X, sperm carry X or Y in equal numbers; a Punnett square shows XX and XY combinations occur equally often, giving about a 50% chance of a male baby
Mark scheme for Question 6 [6 marks]
Question 6[6 marks]
Answer or workingMarks
the two populations are geographically isolated and cannot interbreedB1
each population experiences different environmental conditions or independently accumulates different mutationsB1
natural selection acts differently on each population, favouring different characteristics in eachB1
over many generations the two populations become increasingly genetically differentB1
eventually, the two populations become so different that they can no longer interbreed to produce fertile offspring, meaning they have become separate speciesB1
scientists can compare DNA sequences between the two populations, and a large enough difference confirms they can no longer be classified as the same speciesB1
Final answer: Geographic isolation stops interbreeding, so each population evolves separately by natural selection until they can no longer produce fertile offspring together, forming two species; comparing their DNA sequences can confirm how different they have become
Mark scheme for Question 7 [6 marks]
Question 7[6 marks]
Answer or workingMarks
using ratio = 2900 / 120M1
approximately 24 times more energyA1
during vigorous exercise, the heart and lungs cannot supply oxygen to the muscles fast enough to meet the high demand for aerobic respirationB1
anaerobic respiration not requiring oxygen, so it can continue to release some energy even when oxygen supply is insufficientB1
this allowing muscle contraction (and exercise) to continue, even though anaerobic respiration releases far less energy per glucose moleculeB1
the resulting build-up of lactic acid needing to be broken down using oxygen later (an oxygen debt repaid during recovery)B1
Final answer: Aerobic respiration releases about 24 times more energy than anaerobic respiration from the same glucose; muscles still respire anaerobically during vigorous exercise because oxygen cannot be supplied fast enough, and this lets contraction continue despite being far less efficient, though it creates an oxygen debt that must later be repaid
Mark scheme for Question 8 [6 marks]
Question 8[6 marks]
Answer or workingMarks
to focus on a near object, the ciliary muscles contractB1
this reduces the tension in the suspensory ligaments (they become slack)B1
the lens, no longer being pulled taut, becomes fatter/more rounded, increasing its power to refract (bend) lightB1
this greater refraction is needed to focus light from a nearby object (which diverges more) onto the retinaB1
to focus on a distant object, the ciliary muscles instead relax and the suspensory ligaments become tautB1
this pulls the lens thin, reducing its power, which is enough to focus the more parallel light rays from a distant objectB1
Final answer: For a near object, ciliary muscles contract, slackening the suspensory ligaments so the lens becomes fatter and more powerful, refracting light strongly enough to focus it on the retina; for a distant object the ciliary muscles relax, the ligaments pull the lens thin, and its lower power is enough to focus the more parallel light